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244 k human cpg island microarrays  (Agilent technologies)


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    Agilent technologies 244 k human cpg island microarrays
    Tumor hypermethylation of FOXB2 and FOXF1. ( A , B ) Bisulfite sequence results for 12 BRAF wildtype tumors and 8 BRAF mutant tumors, separated by the horizontal red line. Schematic display of the BSA region with <t>CpG</t> locations therein shown on top (blue). Sample IDs are given on the 5' end of the BSA region. Each circle depicts a CpG. Color code: gray = ND, white = 0% to 20%, yellow = 20% to 40%, orange = 40% to 60%, red > 60% methylation. ( C ) Boxplot showing average methylation percentage over all detected CpGs in BRAF wildtype and BRAF V600E tumors for FOXB2 (left) and FOXF1 (right). The box indicates the 25 and 75 percentiles, with the median shown in bold. Upper and lower outliers are shown as red and purple asterisks, respectively. ( D ) Schematic display of FOXB2 (top) and FOXF1 (bottom) loci depicting the location of the BSA regions in relation to MseI fragments detected on the Agilent array (significant fragments marked red, not significant as black). <t>CpG</t> <t>islands</t> are shown in green, and the BSA region is shown in blue.
    244 K Human Cpg Island Microarrays, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/244 k human cpg island microarrays/product/Agilent technologies
    Average 90 stars, based on 1 article reviews
    244 k human cpg island microarrays - by Bioz Stars, 2026-05
    90/100 stars

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    1) Product Images from "BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer"

    Article Title: BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer

    Journal: Clinical Epigenetics

    doi: 10.1186/1868-7083-5-2

    Tumor hypermethylation of FOXB2 and FOXF1. ( A , B ) Bisulfite sequence results for 12 BRAF wildtype tumors and 8 BRAF mutant tumors, separated by the horizontal red line. Schematic display of the BSA region with CpG locations therein shown on top (blue). Sample IDs are given on the 5' end of the BSA region. Each circle depicts a CpG. Color code: gray = ND, white = 0% to 20%, yellow = 20% to 40%, orange = 40% to 60%, red > 60% methylation. ( C ) Boxplot showing average methylation percentage over all detected CpGs in BRAF wildtype and BRAF V600E tumors for FOXB2 (left) and FOXF1 (right). The box indicates the 25 and 75 percentiles, with the median shown in bold. Upper and lower outliers are shown as red and purple asterisks, respectively. ( D ) Schematic display of FOXB2 (top) and FOXF1 (bottom) loci depicting the location of the BSA regions in relation to MseI fragments detected on the Agilent array (significant fragments marked red, not significant as black). CpG islands are shown in green, and the BSA region is shown in blue.
    Figure Legend Snippet: Tumor hypermethylation of FOXB2 and FOXF1. ( A , B ) Bisulfite sequence results for 12 BRAF wildtype tumors and 8 BRAF mutant tumors, separated by the horizontal red line. Schematic display of the BSA region with CpG locations therein shown on top (blue). Sample IDs are given on the 5' end of the BSA region. Each circle depicts a CpG. Color code: gray = ND, white = 0% to 20%, yellow = 20% to 40%, orange = 40% to 60%, red > 60% methylation. ( C ) Boxplot showing average methylation percentage over all detected CpGs in BRAF wildtype and BRAF V600E tumors for FOXB2 (left) and FOXF1 (right). The box indicates the 25 and 75 percentiles, with the median shown in bold. Upper and lower outliers are shown as red and purple asterisks, respectively. ( D ) Schematic display of FOXB2 (top) and FOXF1 (bottom) loci depicting the location of the BSA regions in relation to MseI fragments detected on the Agilent array (significant fragments marked red, not significant as black). CpG islands are shown in green, and the BSA region is shown in blue.

    Techniques Used: Sequencing, Mutagenesis, Methylation



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    Tumor hypermethylation of FOXB2 and FOXF1. ( A , B ) Bisulfite sequence results for 12 BRAF wildtype tumors and 8 BRAF mutant tumors, separated by the horizontal red line. Schematic display of the BSA region with <t>CpG</t> locations therein shown on top (blue). Sample IDs are given on the 5' end of the BSA region. Each circle depicts a CpG. Color code: gray = ND, white = 0% to 20%, yellow = 20% to 40%, orange = 40% to 60%, red > 60% methylation. ( C ) Boxplot showing average methylation percentage over all detected CpGs in BRAF wildtype and BRAF V600E tumors for FOXB2 (left) and FOXF1 (right). The box indicates the 25 and 75 percentiles, with the median shown in bold. Upper and lower outliers are shown as red and purple asterisks, respectively. ( D ) Schematic display of FOXB2 (top) and FOXF1 (bottom) loci depicting the location of the BSA regions in relation to MseI fragments detected on the Agilent array (significant fragments marked red, not significant as black). <t>CpG</t> <t>islands</t> are shown in green, and the BSA region is shown in blue.
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    Tumor hypermethylation of FOXB2 and FOXF1. ( A , B ) Bisulfite sequence results for 12 BRAF wildtype tumors and 8 BRAF mutant tumors, separated by the horizontal red line. Schematic display of the BSA region with <t>CpG</t> locations therein shown on top (blue). Sample IDs are given on the 5' end of the BSA region. Each circle depicts a CpG. Color code: gray = ND, white = 0% to 20%, yellow = 20% to 40%, orange = 40% to 60%, red > 60% methylation. ( C ) Boxplot showing average methylation percentage over all detected CpGs in BRAF wildtype and BRAF V600E tumors for FOXB2 (left) and FOXF1 (right). The box indicates the 25 and 75 percentiles, with the median shown in bold. Upper and lower outliers are shown as red and purple asterisks, respectively. ( D ) Schematic display of FOXB2 (top) and FOXF1 (bottom) loci depicting the location of the BSA regions in relation to MseI fragments detected on the Agilent array (significant fragments marked red, not significant as black). <t>CpG</t> <t>islands</t> are shown in green, and the BSA region is shown in blue.
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    Tumor hypermethylation of FOXB2 and FOXF1. ( A , B ) Bisulfite sequence results for 12 BRAF wildtype tumors and 8 BRAF mutant tumors, separated by the horizontal red line. Schematic display of the BSA region with <t>CpG</t> locations therein shown on top (blue). Sample IDs are given on the 5' end of the BSA region. Each circle depicts a CpG. Color code: gray = ND, white = 0% to 20%, yellow = 20% to 40%, orange = 40% to 60%, red > 60% methylation. ( C ) Boxplot showing average methylation percentage over all detected CpGs in BRAF wildtype and BRAF V600E tumors for FOXB2 (left) and FOXF1 (right). The box indicates the 25 and 75 percentiles, with the median shown in bold. Upper and lower outliers are shown as red and purple asterisks, respectively. ( D ) Schematic display of FOXB2 (top) and FOXF1 (bottom) loci depicting the location of the BSA regions in relation to MseI fragments detected on the Agilent array (significant fragments marked red, not significant as black). <t>CpG</t> <t>islands</t> are shown in green, and the BSA region is shown in blue.
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    Tumor hypermethylation of FOXB2 and FOXF1. ( A , B ) Bisulfite sequence results for 12 BRAF wildtype tumors and 8 BRAF mutant tumors, separated by the horizontal red line. Schematic display of the BSA region with <t>CpG</t> locations therein shown on top (blue). Sample IDs are given on the 5' end of the BSA region. Each circle depicts a CpG. Color code: gray = ND, white = 0% to 20%, yellow = 20% to 40%, orange = 40% to 60%, red > 60% methylation. ( C ) Boxplot showing average methylation percentage over all detected CpGs in BRAF wildtype and BRAF V600E tumors for FOXB2 (left) and FOXF1 (right). The box indicates the 25 and 75 percentiles, with the median shown in bold. Upper and lower outliers are shown as red and purple asterisks, respectively. ( D ) Schematic display of FOXB2 (top) and FOXF1 (bottom) loci depicting the location of the BSA regions in relation to MseI fragments detected on the Agilent array (significant fragments marked red, not significant as black). <t>CpG</t> <t>islands</t> are shown in green, and the BSA region is shown in blue.
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    Image Search Results


    Tumor hypermethylation of FOXB2 and FOXF1. ( A , B ) Bisulfite sequence results for 12 BRAF wildtype tumors and 8 BRAF mutant tumors, separated by the horizontal red line. Schematic display of the BSA region with CpG locations therein shown on top (blue). Sample IDs are given on the 5' end of the BSA region. Each circle depicts a CpG. Color code: gray = ND, white = 0% to 20%, yellow = 20% to 40%, orange = 40% to 60%, red > 60% methylation. ( C ) Boxplot showing average methylation percentage over all detected CpGs in BRAF wildtype and BRAF V600E tumors for FOXB2 (left) and FOXF1 (right). The box indicates the 25 and 75 percentiles, with the median shown in bold. Upper and lower outliers are shown as red and purple asterisks, respectively. ( D ) Schematic display of FOXB2 (top) and FOXF1 (bottom) loci depicting the location of the BSA regions in relation to MseI fragments detected on the Agilent array (significant fragments marked red, not significant as black). CpG islands are shown in green, and the BSA region is shown in blue.

    Journal: Clinical Epigenetics

    Article Title: BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer

    doi: 10.1186/1868-7083-5-2

    Figure Lengend Snippet: Tumor hypermethylation of FOXB2 and FOXF1. ( A , B ) Bisulfite sequence results for 12 BRAF wildtype tumors and 8 BRAF mutant tumors, separated by the horizontal red line. Schematic display of the BSA region with CpG locations therein shown on top (blue). Sample IDs are given on the 5' end of the BSA region. Each circle depicts a CpG. Color code: gray = ND, white = 0% to 20%, yellow = 20% to 40%, orange = 40% to 60%, red > 60% methylation. ( C ) Boxplot showing average methylation percentage over all detected CpGs in BRAF wildtype and BRAF V600E tumors for FOXB2 (left) and FOXF1 (right). The box indicates the 25 and 75 percentiles, with the median shown in bold. Upper and lower outliers are shown as red and purple asterisks, respectively. ( D ) Schematic display of FOXB2 (top) and FOXF1 (bottom) loci depicting the location of the BSA regions in relation to MseI fragments detected on the Agilent array (significant fragments marked red, not significant as black). CpG islands are shown in green, and the BSA region is shown in blue.

    Article Snippet: Cy5- or Cy3-labeled amplicons, representing methylated DNA fragments derived from tumor and normal samples, were co-hybridized to the Agilent 244 k human CpG island microarrays (#G4492A, Agilent Technologies) in a dye-swap setup.

    Techniques: Sequencing, Mutagenesis, Methylation